Dynamic Brain Circuits in Health and Disease

The fundamental mission of Neuroscience is to take molecular and cellular information, together with mapping pathways in the brain, to understand behavior.

A central focus of this research at UBC is the study of brain connections and their dynamic changes during development, learning and how they are altered in disease. Mapping the brain’s vital wiring diagram called the “connectome” represents the structural and functional circuits between brain cells that underlies all brain function. Virtually all aspects of brain imaging from animal synapse work to human PET and MRI reflect activity within these connections.

The main goals of the Dynamic Brain Circuits in Health and Disease cluster are:

1) to understand brain circuit connections and their changes in diseases and the at-risk brain;

2) to model brain disease to establish mechanistic insights; 

3) to exploit new knowledge to repair the brain with novel therapeutic approaches.

View website

Researchers in the Cluster