UBC researchers are leading 47 projects awarded a total of $38.3 million through the Canadian Institutes of Health Research (CIHR) Project Grants: Spring 2022 competition.
In total, the Project Grants: Spring 2022 competition approved 405 research grants, plus 2 bridge grants, for a total investment of approximately $325M. In addition, 61 priority announcement grants were funded for a total amount of $10,779,207 and 16 supplemental prizes were awarded for a total of $1,060,000
- UBC researchers are leading 46 projects awarded Project Grants of $38.2 million.
- One UBC-led project was awarded a priority announcement grant of $0.1 million
UBC-Led Project Grants
- Automatic Assessment of Aortic Stenosis with Point of Care Ultrasound
Principal Investigator(s): Abolmaesumi, Purang (Electrical and Computer Engineering); Tsang, Michael Y (Cardiology); Tsang, Teresa S (Cardiology)
Research Institution: UBC
- Development of second-generation radiopharmaceuticals targeting the C-X-C chemokine receptor 4 for imaging and therapy of hematological cancers
Principal Investigator(s): Benard, Francois (Radiology)
Research Institution: BC Cancer, part of PHSA (Vancouver)
*Conditionally funded at time of posting
- Assembly and annotation of genomes, transcriptomes, and metagenomes
Principal Investigator(s): Birol, Inanc (Medical Genetics)
Research Institution: BC Cancer, part of PHSA (Vancouver)
- An intersectional investigation of women's experiences of overlapping overdose and COVID-19 public health crises
Principal Investigator(s): Boyd, Jade (Medicine)
Research Institution: UBC
- Gamifying neuro rehabilitation: Can we predict who will benefit?
Principal Investigator(s): Boyd, Lara (Physical Therapy)
Research Institution: UBC
- Traffic-Related Air Pollution, Inhaled Corticosteroids and Host Defence Response in COPD
Principal Investigator(s): Carlsten, Christopher (School of Population and Public Health); Mookherjee, Neeloffer (University of Manitoba)
Research Institution: UBC
- A specialized neural circuit representing novelty on behavioural timescales
Principal Investigator(s): Cembrowski, Mark S (Cellular & Physiological Sciences)
Research Institution: UBC
- Targeting synaptic organizers in neuropsychiatric disorders
Principal Investigator(s): Craig, Ann Marie (Psychiatry)
Research Institution: UBC
- Development of LNP/mRNA systems for direct transfection and generation of functional Chimeric Antigen Receptor (CAR) T-cells in-vivo for treatment of blood and other cancer cell types
Principal Investigator(s): Cullis, Pieter (Biochemistry and Molecular Biology)
Research Institution: UBC
*Conditionally funded at time of posting
- Leveraging TCR reactivity to improve CAR T therapy
Principal Investigator(s): Evgin, Laura E (Medical Genetics)
Research Institution: BC Cancer, part of PHSA (Vancouver)
- Pax6 regulation of glutamatergic lineages in cerebellar development
Principal Investigator(s): Goldowitz, Daniel (Medical Genetics); Pavlidis, Paul (Psychiatry, Michael Smith Laboratories)
Research Institution: BC Children's Hospital Research Institute
- Novel mechanisms and therapeutic approach for aging-related pruritus
Principal Investigator(s): Granville, David J (Pathology and Laboratory Medicine)
Research Institution: UBC
- Determining the role of FMRP complexes in autism-relevant gene expression
Principal Investigator(s): Greenblatt, Ethan J (Biochemistry and Molecular Biology)
Research Institution: UBC
- Transcriptional Drivers of the Hepatic Lineage
Principal Investigator(s): Hoodless, Pamela, A (Medical Genetics, School of Biomedical Engineering)
Research Institution: BC Cancer, part of PHSA (Vancouver)
*Conditionally funded at time of posting
- Pre-clinical development of broad-spectrum antiviral strategies against human respiratory viruses of pandemic concern
Principal Investigator(s): Jean, François (Microbiology and Immunology); Boudreault, Pierre-Luc (Université de Sherbrooke); Leduc, Richard (Université de Sherbrooke)
Research Institution: UBC
- Clonal interactions in myeloid malignancy
Principal Investigator(s): Karsan, Aly (Pathology and Laboratory Medicine)
Research Institution: BC Cancer, part of PHSA (Vancouver)
- Role of SASH1 in generation of hematopoietic stem cells
Principal Investigator(s): Karsan, Aly (Pathology and Laboratory Medicine)
Research Institution: BC Cancer, part of PHSA (Vancouver)
- Applying Research about the Social/Medical Spending Ratio to Federal and Provincial Budget Allocations Between Ministries
Principal Investigator(s): Kershaw, Paul W (School of Population and Public Health); Hennessy, Trish (Canadian Centre for Policy Alternatives)
Research Institution: UBC
- Targeting lung microbiome for developing early detection and intervention strategies for lung cancer
Principal Investigator(s): Lam, Wan L (Pathology and Laboratory Medicine)
Research Institution: B.C. Cancer Research Centre (Vancouver)
*Conditionally funded at time of posting
- Lipid Nanoparticle-Mediated Delivery of CRISPR/Cas9 Gene Editing for Neurological Disorders.
Principal Investigator(s): Leavitt, Blair R (Medical Genetics)
Research Institution: UBC
- Role of BMP2 signaling at the maternal-fetal interface
Principal Investigator(s): Leung, Peter C (Obstetrics & Gynaecology); Beristain, Alexander G (Obstetrics & Gynaecology)
Research Institution: UBC
*Conditionally funded at time of posting
- Next-generation GRPR-targeting radiopharmaceuticals with improved in vivo stability and minimized pancreas uptake
Principal Investigator(s): Lin, Kuo-Shyan (Radiology)
Research Institution: BC Cancer, part of PHSA (Vancouver)
- Health and neurodevelopmental trajectories of children and adolescents born at preterm and term gestation
Principal Investigator(s): Lisonkova, Sarka (Obstetrics & Gynaecology); Razaz, Neda (Karolinska Institutet)
Research Institution: UBC
- Atrial fibrillation stroke prevention: New insights from anticoagulant adherence thresholds and trajectories
Principal Investigator(s): Loewen, Peter S (Pharmaceutical Sciences)
Research Institution: UBC
- Behaviour-based cell separation to interrogate host cell heterogeneity in CAR-T cell therapies
Principal Investigator(s): Ma, Hongshen (Mechanical Engineering, School of Biomedical Engineering)
Research Institution: UBC
- SinoNasal Microbiota Transfer (SNMT) to treat chronic rhinosinusitis: A randomized, double-blind, placebo-controlled trial
Principal Investigator(s): Manges, Amee R (School of Population and Public Health); Javer, Amin R (Surgery)
Research Institution: UBC
- A Study of Reduced Dosing of the Nonavalent HPV Vaccine in Women Living with HIV
Principal Investigator(s): Money, Deborah M (Obstetrics & Gynaecology)
Research Institution: UBC
- Role of MERCs and Mitophagy in Cancer Progression
Principal Investigator(s): Nabi, Ivan R (Cellular & Physiological Sciences)
Research Institution: UBC
- Traumatic brain injury and cerebral small vessel disease in a vulnerably housed cohort, a prelude to early neurodegeneration and dementia
Principal Investigator(s): Panenka, William J (Psychiatry); Field, Thalia S (Medicine); Thornton, Allen E (SFU); Wellington, Cheryl L (Pathology and Laboratory Medicine)
Research Institution: UBC
- Targeting inflammatory and neurodegenerative pathways relevant to progression in the NR1H3 (LXRA) R415Q model of primary progressive multiple sclerosis
Principal Investigator(s): Quandt, Jacqueline A (Pathology and Laboratory Medicine)
Research Institution: UBC
- Quantitative Susceptibility Mapping from Clinical Phase Data
Principal Investigator(s): Rauscher, Alexander (Pediatrics)
Research Institution: UBC
- Understanding sex differences in the neuronal control of whole-body fat storage and breakdown
Principal Investigator(s): Rideout, Elizabeth J (Cellular & Physiological Sciences)
Research Institution: UBC
- Family Matters: Engaging Loved Ones to Prevent Overdose Deaths in Semi-Urban and Rural Communities
Principal Investigator(s): Salmon, Amy L (School of Population and Public Health); Hawkins, Jennifer (Centre for Health Evaluation & Outcome Sciences)
Research Institution: Centre for Health Evaluation & Outcome Sciences (Vancouver, BC)
- Peers Actively Involved in Rehabilitation: Transforming Traumatic Brain Injury Rehabilitation (PAIR TBI)
Principal Investigator(s): Schmidt, Julia (Occupational Science & Occupational Therapy)
Research Institution: UBC
- Mechanisms underlying the bronchodilatory effect of deep inspiration in health and asthma: from airway smooth muscle to the whole lung
Principal Investigator(s): Seow, Chun Y (Pathology and Laboratory Medicine)
Research Institution: UBC
- A bioengineering platform to promote safe cell therapies
Principal Investigator(s): Shakiba, Nika (School of Biomedical Engineering); Goyal, Sidhartha (University of Toronto)
Research Institution: UBC
*Conditionally funded at time of posting
- An evaluation of the health, criminal justice, and service use outcomes of the Ministry of Health assuming responsibility for prison health care services in BC (PRISM-BC)
Principal Investigator(s): Slaunwhite, Amanda K (School of Population and Public Health); Nicholls, Tonia L (School of Population and Public Health); Schütz, Christian G (Psychiatry)
Research Institution: UBC
- The Cedar Project: Strengthening Our Spirit Intervention for Indigenous peoples who use drugs in two Canadian cities
Principal Investigator(s): Spittal, Patricia M (School of Population and Public Health)
Research Institution: UBC
- Drug overdose after departure from hospital against medical advice
Principal Investigator(s): Staples, John A (Medicine)
Research Institution: UBC
- Digital self-tracking and self-testing for early detection of endometrial cancer
Principal Investigator(s): Talhouk, Aline (Obstetrics & Gynecology); Anglesio, Michael S (Obstetrics & Gynaecology); Hill, Janet E (University of Saskatchewan); Money, Deborah M (Obstetrics & Gynecology); Tinker, Anna (Medicine)
Research Institution: UBC
- Mechanisms of endogenous retrovirus-mediated antiviral immunity against genital herpes simplex virus 2 infection and disease.
Principal Investigator(s): Tokuyama, Maria (Microbiology & Immunology)
Research Institution: UBC
- Fate and function of mesenchymal progenitors within the medulloblastoma tumour microenvironment
Principal Investigator(s): Underhill, Michael (Cellular & Physiological Sciences, School of Biomedical Engineering)
Research Institution: UBC
- Mesenchymal progenitors in liver fibrosis - quiescence as a therapeutic target
Principal Investigator(s): Underhill, Michael (Cellular & Physiological Sciences, School of Biomedical Engineering)
Research Institution: UBC
- Regulatory mechanisms of voltage-gated calcium channels
Principal Investigator(s): Van Petegem, Filip (Biochemistry & Molecular Biology)
Research Institution: UBC
- Structural and functional investigation of Junctophilins in health and disease
Principal Investigator(s): Van Petegem, Filip (Biochemistry & Molecular Biology)
Research Institution: UBC
- Clinical-biomarker predictors of outcome after endometriosis surgery
Principal Investigator(s): Yong, Paul (Obstetrics & Gynecology); Anglesio, Michael S (Obstetrics & Gynecology); Howard, Amanda F (Nursing); Mohamed, Ali Bedaiwy (Obstetrics and Gynecology); Talhouk, Aline (Obstetrics & Gynecology)
Research Institution: UBC
Full list of Project Grant recipients
Note: conditional awards will appear in the CIHR online listing once conditions are satisfied
UBC-LED PROJECTS: PRIORITY ANNOUNCEMENT GRANTS
Priority Announcement: Epigenetics/epigenomics in human health or disease
- Blood Epigenetic Age Biomarkers and Health Outcomes in COPD
Principal Investigator(s): Sin, Donald (Medicine), Leung, Janice (Medicine)
Research Institution: UBC
Full list of Priority Announcement grant recipients