July 18, 2024
A total of 52 projects led by UBC researchers were awarded $34.2 million in combined funding through the Canadian Institutes of Health Research Project Grant: Spring 2024 competition.
- UBC researchers are leading 39 projects awarded Project Grants totaling $32.9 million
- 13 projects led by UBC researchers were awarded Priority Announcement Grants totaling $1.3 million
On a national level, CIHR approved a total of 373 research grants, for a total investment of approximately $325 million. In addition, 68 priority announcement grants were funded for a total amount of $7,600,000 and 5 supplemental prizes were awarded for a total of $210,000
CIHR PROJECT GRANT AWARD ANNOUNCEMENT
UBC-Led Project Grants
- Abdelrahman, Khaled (Anesthesiology, Pharmacology and Therapeutics)
The contribution of metabotropic glutamate receptor 5 to cerebral blood flow homeostasis in Alzheimer's disease
- Altshuler, Douglas (Zoology)
Visual control of complex locomotion by the cerebellum
- Bally, Marcel (Experimental Therapeutics)
Co-PI(s): Evgin, Laura (Medical Genetics)
Copper Associated Immunogenic Cell Death: Improving the Therapeutic Potential of Immune Check Point Inhibitors for the Treatment of Metastatic Bladder Cancer
- Bashashati, Ali (Pathology and Laboratory Medicine)
Co-PI(s): Black, Peter (Urological Sceinces); Wang, Gang (Pathology and Laboratory Medicine)
aRtificial intelligence-driven computational pathology platform for blAdder Cancer subTyping (REACT)
- Bergstrom, Kirk (Biology, UBC Okanagan)
Mechanisms and therapeutic potential of microbial-driven mucus production by proximal colon goblet cells in colitis
- Brubacher, Jeffrey (Emergency Medicine)
The impact of 12-hour overnight shifts on nurses' driving safety: A high-fidelity driver simulator study.
- Brubacher, Jeffrey (Emergency Medicine)
The impact of medical cannabis on driving safety: A driving simulation study.
- Daugaard, Mads (Urologic Sciences)
An integrated AI-powered platform for cell analytics
- De Boer, Carl (School of Biomedical Engineering)
Identifying altered gene regulatory network states and underlying mechanisms in atrial fibrillation, a model polygenic disease
- Dong, Xuesen (Urologic Sciences)
Lin28b as a therapeutic target for prostate cancer progression
- Eng, Janice (Physical Therapy)
Co-PI(s): Manyanga, Taru (Physical Therapy); Pollock, Courtney (Physical Therapy); Sakakibara, Brodie (Occupational Science and Occupational Therapy / Southern Medical Program, UBC Okanagan)
Implementation research to improve scale-up of the delivery of evidence-based community exercise programs for stroke
- Fedida, David (Anesthesiology, Pharmacology and Therapeutics)
Mechanisms of potassium channel arrhythmias
- Francis, Gordon (Medicine)
Arterial smooth muscle cell lysosomal acid lipase as a novel target for atherosclerosis treatment and prevention
- Frangou, Sophia (Psychiatry)
Network-Brain Age: Enhancing spatial precision of accelerated aging
- Gill, John (Nephrology)
Co-PI(s): Lan, James (Nephrology); Suri, Rita (McGill University)
A prospective interventional study to prevent allosensitization in patients who have failed a first kidney transplant
- Hackett, Tillie-Louise (Anesthesiology, Pharmacology and Therapeutics)
Co-PI(s): Ryerson, Christopher (Medicine)
Integration of multi-resolution imaging to improve the diagnosis and treatment of fibrotic interstitial lung diseases
- Hanley, Gillian (Obstetrics & Gynaecology)
Long term development in children exposed in utero to attention deficit hyperactivity disorder and stimulant medication
- Huntsman, David (Pathology and Laboratory Medicine)
DICER1 tumour predisposition syndrome: dissecting the oncogenic mechanisms with a novel lineage-trackable genetically engineered mouse model
- Ibrahim, Mohamed (School of Social Work)
Strengthening mental health services through enhancing the capacity of health workers in Somalia (MH Care-Somalia)
- Jamieson, Amy (Obstetrics & Gynaecology)
Co-PI(s): McAlpine, Jessica (Obstetrics & Gynaecology)
STRIVE Study: STRatIfication of Vulvar squamous cell carcinoma by HPV and p53 status to guide Excision
- Karim, Mohammad (School of Population and Public Health)
Developing an Epidemiological Tool for Early Detection: A Risk Prediction Algorithm for Prodromal Multiple Sclerosis
- Kizhakkedathu, Jayachandran (Pathology and Laboratory Medicine)
Co-PI(s): Withers, Stephen (Chemistry)
Transfusion Without Blood Typing: Enzymatic Glycoengineering Towards 'True' Universal Blood
- Li, Hongbin (Chemistry)
Molecular Mechanism for the Regulation of Titin Elasticity and Myocardial Stiffness by Oxidative Stress
- Lima, Viviane (Medicine)
Co-PI(s): Brumme, Zabrina (Simon Fraser University)
Persistent Low-Level HIV Viremia During Antiretroviral Therapy: Origins and Clinical Consequences
- McNagny, Kelly (Medical Genetics / School of Biomedical Engineering)
Neonatal ILCs Sculpt Long-term Adult Immune Response
- Michalak, Erin (Psychiatry)
Co-PI(s): Barnes, Steven (Psychology)
Evaluating the efficacy of the PolarUs app on quality of life outcomes in people with bipolar disorder
- Moritz, Orson (Ophthalmology)
Genetic and environmental modulators of disease mechanisms in retinitis pigmentosa.
- Pesut, Barbara (School of Nursing, UBC Okanagan)
Co-PI(s): Hassan, Eman (Medicine); Seow, Hsien-Yeang (McMaster University)
Evaluating a Compassionate Community Volunteer Navigation Approach to Supporting Older Persons Living with Life-Limiting Illness and Frailty in Rural Communities.
- Pouladi, Mahmoud (Medical Genetics)
Probing the Role of Claudin-11 Mutations in Hypomyelinating Leukodystrophy
- Rankin, Catharine (Psychology)
In vivo functional characterization of Parkinson's disease linked genes and identification of the best candidate genes of Parkinson's Disease GWAS loci using Caenorhabditis elegans.
- Reid, Gregor (Pediatrics)
Harnessing infection-associated modifiers of paediatric acute lymphoblastic leukaemia progression for therapeutic benefit
- Saewyc, Elizabeth (School of Nursing)
Fifteen year trends in racism, enacted stigma, and mental health among South Asian LGBQ+ adolescents: The impact of inclusive schools in British Columbia
- Silverberg, Noah (Psychology)
REhabilitation of MEMory symptoms after BRain concussion (REMEMBR trial)
- Sly, Laura (Pediatrics)
Co-PI(s): Brumer, Harry (Michael Smith Laboratories / Chemistry)
Bespoke plant glycoconjugates to improve Inflammatory Bowel Disease treatment through gut-microbiota-mediated drug targeting
- Stirling, Peter (Medical Genetics / Terry Fox Laboratory)
Development and application of novel FEN1 endonuclease inhibitors
- Velenosi, Thomas (Faculty of Pharmaceutical Sciences)
Characterizing diacetylspermine as a biomarker of drug response and precision treatment in triple-negative breast cancer
- Wisnovsky, Simon (Faculty of Pharmaceutical Sciences)
Co-PI(s): Williams, Karla (Faculty of Pharmaceutical Sciences)
T-cell glyco-immune checkpoints as next-generation targets for cancer immunotherapy
- Zandstra, Peter (Michael Smith Laboratories / School of Biomedical Engineering)
Gastruloid Engineering: Precision Organoid Design for Developmental and Disease Modeling
- Zoubeidi, Amina (Urologic Sciences)
Interplay between ASCL1 and chromatin remodeling complex in prostate cancer lineage plasticity
FULL LIST OF PROJECT GRANT AWARDEES
UBC Led-Priority Announcements
- Foster, Leonard (Michael Smith Laboratories)
Development and Commercialization of a Safe and Effective Mpox Subunit Vaccine with Global Impact
Priority Announcement Area: Pandemic Preparedness and Health Emergencies Research
- Hohl, Corinne (Emergency Medicine)
Co-PI(s): Archambault, Patrick (Université Laval); Brooks, Steven (Queen’s University); Chandra, Kavish (Dalhousie University); Daoust, Raoul (Université de Montréal); Dong, Kathryn (University of Alberta); Fok, Patrick (Dalhousie University); Grunau, Brian (Emergency Medicine); Jelic, Tomislav (University of Manitoba); Kestler, Andrew (Emergency Medicine); Lock, Kurt (BCCDC); Lysyshyn, Mark (School of Population and Public Health / Vancouver Coastal Health); McRae, Andrew (University of Calgary); Moe, Jessica (Emergency Medicine); Morrison, Laurie (University of Toronto); Olszynski, Paul (University of Saskatchewan); Orkin, Aaron (University of Toronto); Perry, Jeffrey (University of Ottawa); Rosychuk, Rhonda (University of Alberta); Stone-McLean, Jordan (Memorial University of Newfoundland)
Optimizing outcomes for patients presenting to emergency departments with opioid poisoning
Priority Announcement Area: Pandemic Preparedness and Health Emergencies Research
- Kim, Hugh (Oral Biological & Medical Sciences)
Pro-inflammatory platelet signaling: identifying novel therapeutic targets for periodontitis
Priority Announcement Area: IMHA: Oral Health
- Lynn, Francis (Surgery / School of Biomedical Engineering)
Co-PI(s): Verchere, Bruce (Pathology and Laboratory Medicine), Levings, Megan (Surgery / School of Biomedical Engineering)
Building better beta cells in order to improve stem cell-derived islet transplantation outcomes
Priority Announcement Area: Nutrition, Metabolism and Diabetes
*Conditional award at time of announcement
- Maxwell, Christopher (Pediatrics)
Elucidate the targetable mechanisms underpinning the development of a pregnancy-associated breast cancer in BRCA1 mutation carriers.
Priority Announcement Area: Breast Cancer Prevention & Early Detection
- McKevitt, Elaine (Surgery)
Oncologic, surgical, and patient reported outcomes following breast conserving surgery versus mastectomy in breast cancer patients: a prospective study.
Priority Announcement Area: Breast Cancer Survivorship
- Nacul, Luis (Family Practice)
Epidemiology and impact of myalgic encephalomyelitis and chronic fatigue syndrome (ME/CFS) in Canada: A multi-centre population-based study
Priority Announcement Area: Pandemic Preparedness and Health Emergencies Research
- Ryan, Katherine (Chemistry)
Assembly of a pseudo-peptide active against Gram-negative bacteria
Priority Announcement Area: Antimicrobial Resistance (Bridge Grant)
- Schummers, Laura (Faculty of Pharmaceutical Sciences)
Co-PI(s): Clement, Fiona (University of Calgary); Henry, Bonnie (School of Population and Public Health); Law, Michael (School of Population and Public Health); Nickel, Nathan (University of Manitoba)
Effect of Canada's first universal contraception subsidy on access, pregnancy outcomes, and costs: a population-based controlled interrupted time series study
Priority Announcement Area: Sex and Gender in Health Research (Bridge funding)
- Thiessen, Kellie (Family Practice)
Co-PI(s): Gulbransen, Kristen (University of Manitoba); Price, Roberta (School of Nursing); Skiber, Darci (BC Women's Hospital and Health Centre); Watson, Heather (University of Manitoba)
Through the Cracks: Development of a Psychosocial Perinatal Mentorship Framework, to address escalating maternal mortality rates for pregnant persons with psychosocial comorbidities
Priority Announcement Area: Research in First Nations, Inuit and/or Métis Health
- Tocheva, Elitza (Microbiology and Immunology)
Structural and functional characterization of the type VII secretion system in Mycobacteria
Priority Announcement Area: Antimicrobial Resistance (Bridge Grant)
- Viau, Victor (Cellular and Physiological Sciences)
Sex differences in inflammatory, neuroendocrine and behavioural responses: Impact of corticosteroid-binding globulin deficiency.
Priority Announcement Area: Sex and Gender in Health Research (Bridge funding)
- Whittaker, Jacqueline (Physical Therapy)
The Stop Osteoarthritis (SOAR) Hybrid Effectiveness-Implementation Type 1 Randomized Controlled Trial for Young People at-High-Risk of Early Onset Knee Osteoarthritis
Priority Announcement Area: Female Athlete Health